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Open Positions
Funded PhD Position Available
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Defining Endosome-Lysosomal Network Dysfunction in Neurological Disease
Start Date: September 2026
Duration: 4 years
Funding: Royal Society Studentship (UK students only)
Application Deadline: Sunday, February 15, 2026 at 11:59pm GMT
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About the Project
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Dysfunction in the endosomal-lysosomal network is a key cellular pathology found across human developmental and age-related neurological diseases including Alzheimer's and Parkinson's disease. Our laboratory focuses on developing and applying cutting-edge techniques to achieve a thorough mechanistic dissection of this network, translating acquired knowledge to understand neurological disease.
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This fully funded 4-year PhD studentship will study endosomal-lysosomal network function in the context of human development and age-related neurological disease.
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Training and Techniques: You will receive comprehensive training in core cell biology research techniques including biochemistry (especially quantitative proteomics), molecular approaches (including AlphaFold and structural methods), and cell biology using gene-edited human i3-neurons, fixed and live cell imaging.
The project will be supervised by Prof. Peter Cullen, with collaborative input from other PIs in Bristol and a network of worldwide collaborators.
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We are looking for an enthusiastic and innovative student with a degree in:
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Biochemistry
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Neuroscience
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Molecular Cell Biology
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Medical Science
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Lab Culture: The successful candidate will share the core values of the Cullen lab in collaborative, multidisciplinary and open team science, conducted in a transparent, supportive and relaxed environment.
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Location: Bristol is a centre for molecular cell biology research, and you will benefit from exposure to a wide range of cutting-edge research. The city of Bristol is vibrant, cosmopolitan and culturally diverse, with excellent flight connections to European cities.
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Funding Details
This Royal Society funded studentship includes:
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Annual stipend: £25,000 in year 1, rising to £26,530 in year 4
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Tuition fees fully funded
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Research costs fully funded
Available to UK students only
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How to Apply
For full application details, please visit the FindAPhD listing.
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Alternatively, contact Prof. Pete Cullen for informal inquiries at:
pete.cullen@bristol.ac.uk
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